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(1)Usual Adult Dose for Breast Cancer:
For the treatment of metastatic breast cancer in women and men:
20 to 40 mg orally Dosages greater than 20 mg should be given in divided doses (morning and evening).
For the treatment of women with Ductal Carcinoma in Situ, following breast surgery and radiation:
20 mg orally daily for 5 years.
To reduce the incidence of breast cancer in women at high risk for breast cancer:
20 mg orally daily for 5 years.

(2)Usual Adult Dose for Breast Cancer – Adjuvant:
For the treatment of node-positive breast cancer in postmenopausal women following total mastectomy or segmental mastectomy, axillary dissection, and breast irradiation:
10 mg orally 2 to 3 times a day for 5 years.

(3)Usual Adult Dose for Breast Cancer – Palliative:
10 to 20 mg orally twice a day
A beneficial response may not be evident for several months after initiation of therapy.

(4)Usual Pediatric Dose for McCune-Albright Syndrome:
For use in girls age 2 to 10 years with McCune-Albright Syndrome and precocious puberty:
20 mg once a day. The duration of treatment is up to 12 months.

(5)Usual Pediatric Dose for Precocious Puberty
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