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Polypeptide MOTS-c, short for Mitochondrial-derived Short Open Reading Frame-c, is a recently discovered bioactive peptide with promising implications for metabolic health. The peptide was first identified in 2015 by a team of researchers studying the effects of exercise on mitochondrial function. It originates from a unique portion of the mitochondrial genome, known as the 12S rRNA, and is conserved across species, suggesting its evolutionary significance.

MOTS-c and semaglutide  

MOTS-c and semaglutide are both peptides that have been studied for their potential effects on metabolic health, but they are distinct in their mechanisms and applications.

While both MOTS-c and semaglutide have shown promising effects in metabolic health, they have different mechanisms of action and applications. MOTS-c is still under investigation, and more research is needed to fully understand its therapeutic potential and safety. Semaglutide, on the other hand, is an established medication used for the management of type 2 diabetes. If you are considering any of these therapies, it is crucial to consult with a healthcare professional to determine the most appropriate treatment approach based on your specific health needs and medical history.